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RStudio fitting generalized linear model function
Fitting Generalized Linear Model Function, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A <t>generalized</t> <t>linear</t> <t>model</t> <t>(GLM)</t> accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.
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A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A <t>generalized</t> <t>linear</t> <t>model</t> <t>(GLM)</t> accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.
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A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A <t>generalized</t> <t>linear</t> <t>model</t> <t>(GLM)</t> accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.
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A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A <t>generalized</t> <t>linear</t> <t>model</t> <t>(GLM)</t> accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.
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A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A <t>generalized</t> <t>linear</t> <t>model</t> <t>(GLM)</t> accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.
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A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A generalized linear model (GLM) accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.

Journal: PLoS ONE

Article Title: Deep Brain Stimulation Imposes Complex Informational Lesions

doi: 10.1371/journal.pone.0074462

Figure Lengend Snippet: A: Microelectrode recordings were performed in regions of the globus pallidus and thalamus with spike activity that was responsive to passive joint movement. B: Results of experimenter-blinded muscle rigidity scoring for both monkeys at three DBS settings. C and D: Co-registration of pre-operative MRI and post-electrode implantation CT showing DBS electrode location for monkey R (C) and K (D). E and F: Localization of recorded cells obtained from stereotactic navigation software and overlaid on corresponding atlas plates for monkey R (top) and K (bottom) for both the pallidum (E) and the thalamus (F). G: A generalized linear model (GLM) accounting for position, velocity, and acceleration of the joint movement was applied to determine the correlation between kinematics of the joint movement (top row) and spike activity (2 nd row: spike raster, 3 rd row: corresponding rate histogram). Bottom row shows the GLM prediction of firing rate.

Article Snippet: A generalized linear model (GLM) fit function in Matlab (Mathworks, Natick MA) was applied, with Δt=1 ms and covariates of position, velocity, and acceleration in the plane of the tracked limb’s movement ( ).

Techniques: Activity Assay, Software